I have received an email pointing me to www.celltrix.org. This email
and website claims a skin care product using human stem cells in a
cream base for skin regeneration. There is a trial conducted by Dr
Sergey Fluerar. Is there any truth to this claim and any published
information anywhere?
Hit the bullseye on a difficult and highly technical subject!
Thanks that's useful but the critical question is: Can stem cells be
mixed in a face cream, stay extant and then be applied to the face,
attach to the skin and rejuvenate skin and its appearance?
Okay, now we're close to the crux of it! I've read all you've sent me!
Great! The critical questions then are:
How can human stem cells be placed in an oil based carrier and remain
live (extant) for a period of time out of refigeration? What is this
period of time?
What is the maximum temperature for them to tolerate?
If you want more funds or a tip to answer this please advise! You're fantastic!!
Best wishes!
Hi jiaogulan,
Apparently the claim that human stem cells assist in the regeneration
of skin tissue, and other organs, is true. Below are excerpts from
various reliable sources which provide information on this research. I
recommend you read the articles in their entirety.
?Are there potential benefits that could inure from the use of stem
cells? Yes, there are. When asked in an interview, ?What are the
potential benefits of researching these cells,? bioethicist Alta Charo
of the University of Wisconsin (who is a member of the National
Bioethics Advisory Commission to the President), responded:
They could help regrow heart muscle after a heart attack. They could
regrow brain tissues that could be an answer to Alzheimer?s,
Parkinson?s, and Lou Gehrig?s disease. They could be used as a therapy
for burns or to regenerate skin and would help in developing new drugs
(2001, 56[8]:101).?
AP on the Web: Reason & Revelation
http://www.apologeticspress.org/rr/rr2001/r&r0110a.htm
================================================
?For the first time, scientists have coaxed human embryonic stem cells
into becoming three-dimensional tissue structures, a breakthrough that
could pave the way for regenerating organs and tissues to replace
those damaged by disease.?
Apples for Health: Stem Cells Used To Generate Organ Tissue
http://www.applesforhealth.com/OrganDonation/stemgenorgt5.html
================================================
?Stem cells are cells that can develop into mature, specialised cells
in order to generate and regenerate tissue and organs securing the
functions of the human body. A stem cell can divide into identical
copies, a process which in principle can go on indefinitely. The
properties of stem cells depend on their developmental stage and the
source from which they are isolated??
Biokemisk Forening: Human stem cell research under debate in Denmark
http://www.biokemi.org/biozoom/2003_2/bz_0203g.htm
================================================
?Human stem cells hold great promise in health care. Stem cells have
the ability to divide without limit and give rise to many specialized
cells. They are best described in the context of normal human
development, which begins when a sperm fertilizes an egg and creates a
single cell that has the potential to form an entire organism. This
fertilized egg is totipotent, meaning that these cells give rise to
all the cells in the body??
Personal MD: Stem Cells Hold Great Promise In Health Care
http://www.personalmd.com/news/stemcells_090700.shtml
================================================
?Recently Xu proved that after being burned, the human body
instinctively uses any remaining tissue to regenerate stem cells,
which then somehow adjust themselves to lead to new skin tissue.
Human stem cells are those that can divide and are now used to
regenerate skin and it is hoped that later these cells can be used to
regenerate other human organs.?
People's Daily: Sci-Edu
http://fpeng.peopledaily.com.cn/200008/21/eng20000821_48646.html
================================================
?The China National Burns Association (West-East) held a press
conference on the "Achievements of Burn Treatments by Skin
Regeneration in China" in Beijing on August 8,2000. The press release
focused on a series of research achievements accomplished by Professor
Rongxiang Xu and his team. Using residual viable burn skin tissue,
they fulfilled the promise of skin regeneration by stem cell culturing
in vivo and in situ and successfully applied the technology in
treating severe and extensive deep 2nd and 3rd degree burn victims.?
MEBO - Breakthrough: Researches on Skin Regeneration and Duplication
by Stem Cell in vivo and in situ
http://www.mebo.com/Eng/news20000808.htm
================================================
================================================
Search criteria:
?human stem cells? skin care regenerate
?human stem cells? ?skin regeneration?
?human stem cells? ?skin care?
?human stem cell? ?skin care? regeneration
?stem cells? ?skin care?
human ?stem cells? ?skin care?
I hope the information provided is helpful. If you have any questions
regarding my answer please don't hesitate to ask before rating it.
Best wishes,
rainbow-ga
Hi jiaogulan,
Thank you for your comments.
After carrying out further research, I realize the information you are
seeking is not readily available on the internet. Therefore, I have
sent out some emails with these inquiries and if and when I receive
responses, I will let you know. You may then want to the post another
question directed to me since you cannot increase the price or tip
once the answer is rated.
I'll keep you informed of my progress.
Best wishes,
rainbow~
Hi jiaogulan,
In regard to your clarification; the following is an excerpt from an
authoritative documentation that I was able to locate regarding
whether human stem cells can be maintained and extant (although not
necessarily in a cream-based mixture).
?Medicine, biotechnology and the understanding of human development
took a huge leap forward this month, as did stock prices of the Geron
Corporation. Geron has financed research at the University of
Wisconsin and Johns Hopkins University that has just culminated in
both teams announcing the identification, isolation and culturing of
human embryonic stem and germ cells. The discovery has enormous
implications for the treatment of diseased tissues, drug testing,
genetic engineering, and the understanding of fetal development and
birth defects. The teams took different approaches. The Wisconsin
group, led by James Thomson, took cells from human embryos created by
in vitro fertilization. Specifically, embryos were cultured to the
blastocyst stage then cell masses were removed and grown separately.
Using mouse feeder cells, the researchers were able to maintain
embryonic stem cells without any specialization developing or cells
dying.?
Brooks/Cole: Universal Human Stem Cells Isolated and Cultured
http://www.brookscole.com/biology_d/special_features/bioUpdates/bioUpdates1298.html#Universal
The patent below is significant in the question on whether stems cells
can be used for regeneration of the skin in the forms of creams,
lotions, etc.
This patent for ?Physiological tissue repair and functional organ
regeneration by cultivation of regenerative stem cells in vivo and in
situ? was filed by Rongxiang Xu.
?What is claimed is:
1.A composition for promoting cell growth, tissue repair and/or organ
regeneration in vivo comprising: a fatty acid-containing oil at a
concentration at least 10% by weight based on the total weight of the
composition; and a sterol compound added to and dissolved in said oil
at a concentration at least 1% by weight based on the total weight of
the composition.
(?)
50.The composition according to claim 1, wherein the composition is in
a form selected from the group consisting of liquid, lotion, cream or
ointment...?
US Patent and Trademark Office
http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=2&f=G&l=50&co1=AND&d=PG01&s1=%22Scutellaria+rehderiana%22&OS=%22Scutellaria+rehderiana%22
This patent was filed and granted. MEBO is the the trademark for The MEBO Group.
?The MEBO Group, pioneers in the research and application of adult
stem cells, was founded by Professor Xu Rong-xiang in 1987. The
research has provided the market with innovative technologies and
products that fulfills the promise of regeneration and repair, human
organs in vivo and in situ. MEBO, is the trademark of MEBO Group.
Research on stem cell regeneration in vivo and in situ was conducted
on the basis of Moist Exposed Burn Therapy (MEBT), an innovative burn
therapy that has been and is currently in worldwide clinical use. With
years of basic research, Professor Rongxiang Xu, the inventor of the
therapy has identified that it was by skin regeneration and
replication from stem cell culturing in situ that MEBT effectively
treats burns. It was also confirmed that subsequent to burn injuries,
the human body has an instinctive ability to trigger residual tissue
in situ to regenerate stem cells, which are then adjusted to give rise
to skin tissue. This significant discovery advances human stem cell
research into the application of organ regeneration and replication by
in vivo and in situ culture of stem cell.?
(?)
?Headquartered in Beijing, the MEBO Group with its international head
office in Los Angeles, is delivering valuable pharmaceutical and skin
care products to its customers. The primary goals of MEBO group are to
satisfy an increasing demand to improve the overall health and
wellbeing of every individual.?
MEBO: Company
http://www.mebo.com/Eng/company-r.htm
MEBO
http://www.mebo.com/Eng/
I hope this helps. If you have any further clarifications, please let
me know and I will do my best to assist you.
Best wishes,
rainbow-ga
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